qHPV vaccine- India’s first indigenous vaccine against cervical cancer

qHPV vaccine- India’s first indigenous vaccine against cervical cancer – Medicoz Community

India accounts for about 1/5th of the world’s
cervical cancer burden. Cervical cancer is almost always associated with Human Papillomavirus (HPV), a double-stranded DNA virus. The strains responsible for malignancy are 16, 18, 31 and 45 with 16 and 18 attributing to >70% of cases. Risk factors influencing the virus include sexual activity and age.

Cervavac is India’s first indigenously prepared quadrivalent HPV (gHPV) vaccine that aims to ensure robust immunity (90% protection) to all:

• Targeted strains: 6, 11, 16 and 18

• Type of vaccine: L1 VLP (L1 capsid Virus-like particles)

• Targeted group: 9-26 years of age, those >44 years of age can take the vaccine post their discussion with a clinician.

• Dose and route of administration: 0.5 ml,
intramuscular

Schedule:

•2 doses – at 0 and 6 months

• 3 doses (recommended for immunocompromised people)- at 0, 1-2 and 6 months

Contraindications:
Pregnancy, known allergic reactions to vaccine component

Storage: 2-8 °C

Reference: https://www.seruminstitute.com/product_pipeline.php, https://www.thelancet.com/journals/lanonc/article/PIIS1470 -2045(22)00567-8/fulltext, https://www.factchecker.in /explained/si-cervavac-indias-1st-hpv-vaccine-for-cervical -cancer-all-you-need-to-know-833460

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qHPV vaccine- India’s first indigenous vaccine against cervical cancer – Medicoz Community