Salt Substitute Best Alternative In Stroke Prevention

Salt Substitute Best Alternative In Stroke Prevention

According to a study called the “Salt Substitute and Stroke Study” (SSaSS) published in the Circulation Journal, replacing conventional salt with salt substitute was a cost-effective strategy for stroke prevention and improved quality of life among the participants of the study.

The SSaSS is a five-year cluster randomized controlled trial that found that replacing regular salt with a reduced-sodium added-potassium salt substitute reduced the risks of stroke, major adverse cardiovascular events, and premature death in people with a history of stroke or uncontrolled high blood pressure in rural China.

The significant health outcome studied was a stroke, and the impacts on quality-adjusted life years were measured (QALYs). The healthcare expenses were derived from participant health insurance information and the literature.

The results of this study stated as follow:
1. The average length of follow-up for the 20,995 individuals was 4.7 years.
2. Conventional salt substitutes lowered the risk of stroke by 14%, and the salt substitute group had 0.054 more QALYs per person on average.
3. The salt replacement group had reduced average expenses compared to the control group.
4. The intervention was dominating in terms of stroke prevention and QALYs gained.
5. Sensitivity tests revealed that these results were robust
6. The salt replacement intervention had a 95.0% chance of being cost-effective and a greater than 99.9% chance of cost-saving.

The authors concluded that the study showed the salt-based substitution’s efficiency for regular salt in stroke prevention and improving the quality of life.

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